OnabotulinumtoxinA (commonly known by the brand name Botox) is a NICE-approved preventive treatment for chronic migraine — defined as 15 or more headache days per month, of which at least eight are migrainous. The treatment involves a series of precise injections administered around the scalp, neck, and shoulder muscles, following a standardised protocol developed specifically for chronic headache disorder.

This treatment is delivered by Dr Kyprianou as part of a structured migraine prevention plan and is typically repeated every 12 weeks. It is one of the most evidence-backed options available for patients whose headache disorder has not responded to oral preventatives.

Suitable for: Adults with chronic migraine who meet clinical criteria and have not benefited sufficiently from at least two other preventive medications.